Oh, yeah, yeah. The opening of new facilities would be subject to the same approval as the Spanish POA. Only EASA would be required to intervene in this case. It would be a significant change through the addition of a new factory, in which it would be necessary to revisit all the points of the standard, especially those relating to the quality system, as well as to see how this new factory is integrated into the Organisation ' s activity in order to verify its suitability.

Below are two useful links regarding applicable regulations, guides and information needed for POA processes:

Civil aviation production organisations, which intend to produce products, parts and equipment accompanied by the certificate of release to service EASA Form 1. The production of these products, parts and equipment is to be appropriate under approval Part 21 Subpart G, as set out in regulatory point 21.A.133 of Part 21 Subpart G of Annex I to Regulation (EU) 748/2012. Only for direct delivery to final customer (e.g. air operator, maintenance workshop, etc.).

Approval of Production Organisation as described in Part 21 Subpart G of Annex I to Regulation (EU) 748/2012. Applicable for those production activities falling within the scope of work of EASA, as set out in Article 2 of Regulation (EU) 2018/1139.

As can be seen on the relevant EASA website (ETSO FAQ), you must be, or have previously applied for, the ADOA (or DOA, if it is an ETSO article which is an APU) and the POA.
 
The DOA/ADOA and ETSO are held by EASA. The POA is handled by AESA as the Spanish Aviation Authority. Therefore, all 3 approvals have to be requested at the same time (approximately), from the respective Authority.
 
A.133 (Eligibility) is essential to remember in relation to the POA: